Safety and Efficacy of Drug-Coated Balloon for Peripheral Artery Revascularization—A Systematic Review and Meta-Analysis

A review of randomized controlled trials and observational cohort studies found in the PubMed, Embase, Cochrane databases through April 2021. In 26 comprising 26,845 patients who were treated by uncoated balloon (UCB) (17,770) or drug-coated (DCB) (9075) angioplasty for lower extremity peripheral arterial disease (LE-PAD), DCB was associated with significantly vessel restenosis, reduction major amputation, decreased need repeat target lesion revascularization compared UCB. Primary patency rate higher underwent angioplasty. Odds all-cause mortality not different between two groups. The use LE-PAD intervention is primary patency, amputation rate, similar as